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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67287255e2c640f302e2a925e47ccb069e0ed0fb181673c32e8b82ad9f19f0b3' 
  AND token = 'hMadXztJEt9C+bI7IhaCK7Qvd5poNW+S74jVntj+dFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}