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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ddc0b201223fe27c9d07edb6255bf66ab55708b753fd8adda47e4a325b8d38' 
  AND token = 'LQ+7rXF6O3LxfteViQhU9WfqUE2usz3VP1ey0Jz+tko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}