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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0385ea4f188f5999ae476a14c5ce4aa1ebd478215cec1010f3798f8366fcd76f' 
  AND token = 'eAeFxEG3ayquwBPDpa+wf1nFhK7nNqFXBXJ5kAMlJ0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}