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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64447f4238615cca0e901cd0ddc61a22372a482ec05e92b9e9cdbd2df006382c' 
  AND token = 'UuF7WowWpj5Igd39ZyqNRFwyaLl3QOaPw9y52HS5I3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}