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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e531bea0bbe43f016e679f40b9a6fe1b2cb8b3544d69223c1e5cad5c007fb224' 
  AND token = 'lSw2hY+ewyvbOW902aFgJLtoXDqRF9DPfHsK8A65k8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}