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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c271199103c727992a4c2622a604b47e33a9b7e7a10e42714f3c4ae17ceb8d86' 
  AND token = 'Yk68+yfQAIUrvZ5M1lrU2TWXGug/LU6R6AVZ3UOnPww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}