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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d09eff27425d1514249110324ef382116bc420f115bf47ef1b64d9465ba9f48' 
  AND token = '2/wDr1XAlMZjv8ezqiPNZs7tKOT2EB6aCKNKV5+vkgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}