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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fb2c280e48dcb165e5e6ff87ccce9b7b454590cc5952a2d0dc65369d169d45e' 
  AND token = 'cTiB2giQP6ptYm+1VipuhN5fP4lxop3LBR3bHMjUzjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}