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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fff2f086ec71f93fc3f04a82e0f8e42c3a0711da47f8ff2a6ade1d743c73c4a' 
  AND token = 'Qc/oy9RrkX95TNGtHKdb2xsgiXhH7oz8EzAxIP+IMkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}