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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc52a51a88eb297a217da4cb079419920112dc449d7e68cf43b9302e324885cf' 
  AND token = 'BYBJWBZI9lrBkIXMI6HSCzAvvljO0nN9l49gAm7VTOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}