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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '548470cfc02a19e6b2835f51212aaa366b4d55aad2fabbc38e24df61f1fc16a1' 
  AND token = 'DN3t/YJvPtMqCYb53K5uE4p9IN+X16K4O0OpQOX7flc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}