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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e6a76bc70fc23096d04304e4d9a54525325497bcbf0a8de8bf1017d635b8aed' 
  AND token = 'VQSoi+Kyf45z6RsiX24YK+dsk2fcCCPEW3s/g8S+S0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}