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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9784e8a848e47835779741889219ba0d0b21b09c9abc8f430a638d70bd1f445f' 
  AND token = '4nW5INUyd9DnbYm+BaihG7YHp6EX/DR4qNQdJir1xsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}