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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f5701ee1781a7e00dd225074930ba3b997da45b9f35065a2b17b1e87de53ac4' 
  AND token = 'jyulik/kXJVcl36mB8OlMPPN5xNYRx4JnFfVbnYq228=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}