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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54922e552f182b317ee82009cab342d3f9c82e6f3b9f13810a2f1c1e1fb7376e' 
  AND token = 'nudslf/ID5i8NqnaaU4cysi3YQ8YWu2RCl30qdAsBYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}