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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f73a4206ea22a5825dcda86dd6ed2410149e438bc100832e97af5de52b98809' 
  AND token = 'gtRPB0PX8EH4EE2GWVtAZzPtTq9QN86xXXZuJ4gIjfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}