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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f66a8e20b68f072289ba3150e61053af6412493cbfbf4ade273a6bce82c74a53' 
  AND token = '5Ig63KHT8lx+nwaSg1alKwfJ5968RrRpaxtWYikqvCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}