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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b007bd9ad40fdcf4b76e23be886d5d90a1a66b03be65433dbda587a94b5840f2' 
  AND token = '6twr1GFSgwzMDiO5X+bEIvJsfr8o3Ofzoxms+7SDK7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}