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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '337ac6407fefdbbe2f06f9998639a7896fde004db48bf74afdf798e4a35a819f' 
  AND token = 'MRCVTUR1TBVkQ0i5QVzZp0tXFjg12HRCKp/bF0DoA14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}