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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed7779a9d9494908c2861b8b7fc9a8f3f77a1b2fe0a64af30fc228ed56c74f78' 
  AND token = '000UTzZ0ttjQIOEGhv4a7ALehnVH8golQfrtpe/Zuk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}