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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c95ae97a35aa2b060337742a2eac69e569c47dbd05045d9541b150da340c1222' 
  AND token = 'm+LRJmnBVJhktVTA7+u1XVO7uKNKwKKK2UCZ2BKd3sY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}