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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73ebbe5a7b9636bdc7f1d253902e1de38720ab9758b9f206a9b099b5bf7a6088' 
  AND token = '2QPpomw0XaT/EbCJUSbv/qrQxet4hSA5yZvaynFx6TY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}