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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e522a49595b2e115966c87250bde5fee1fa30bc14ecf4b5f06c5a423f2fd9165' 
  AND token = '6hVF/d4VOInXlPUhjg+LPu8sQZ5t4ENe5azfEEPBBGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}