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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a4451d6e8442de1788771e9737cef64c806e2c109e65131dcf96ed0ba013d25' 
  AND token = 'IWSY9LrepX8/Fm+KJTf7oVi5iI21S9sdppWLgeioOx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}