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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80faa59b745cbfcab0087cb737a3902de57df3bb6fbfc2ddcfab708c5ee33e6b' 
  AND token = 'NLK7ABKu7NXndQsf79t/4/0tMzZCnQleLp++QZDfO8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}