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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2f315d4ff7bc750920b479918c13c213c41f4fe3826c71025adcaaeb40601e0' 
  AND token = 'mjiJJC1FzO4GRE0HenHlz8AmE1LqEhj0Vsq5AaG4PiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}