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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6017dc20dba3fdf3ac92e8a7cdd0357b7a3944a66faf8011f3a93170deb2f729' 
  AND token = '4S/sXd5Aw1I3UbB8KjR8CHXzIuWZblxhzNDruHw7Nf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}