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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e52ba2d356236415d2ed154a6ab7856ed49fea3e5b7b7cb270d1ca0adbe876f' 
  AND token = '3IqHoPQnk5fQHA/4EpOCBNxDuCALS6tZ6K5wXwhPyVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}