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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6571dd20a9fe692771a08fa4ab35b45227e0da97ea0370afb24d7f1bfe69cb5b' 
  AND token = 'x8plNPZpPWA/fvDv4m5j083j68n9DESna3oggjG1KM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}