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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a5d0ac05f9f9ae0f900655cfa30bbe4a9fdd4aa4c81c63863cba990e2522671' 
  AND token = 'mk3u0o9ErGNEj2wsleaYHzOAOAhwVRL5hMM8fgVgFDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}