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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a1b1f61212c0ab291cf803b556e62861e58f0cacf5443fa40a3e3cb0a01497f' 
  AND token = '1Wb4mEGpIa+DfzkEQp+yda2z9D76Pi75e0iwYKAFrV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}