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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26c9d4ed818b1d9144b10dc45e4263952b29fd7910898ce2d380d80301b727c0' 
  AND token = 'Srb1iel47WqFHwyu5ajI0+x+z9sP7xON+1IglQZNhXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}