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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0378d7f8f539cf803150d99e548b05f18e785c2cec453cbc2ccc60c8ba56c869' 
  AND token = '7LhWsOK7sLHu3l4Ojlg2mwnmdnrB3DnAEh6HsUfUYwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}