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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08ce083d9fb2b53a851a3e98994f0c962a6d3e09f762d57d81e87b566f178c40' 
  AND token = '+5tNpzXS8a7RAP5zvfN5p7BdO/1vZCu+RtqB15u/Tko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}