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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c04b0977192e8fb97b970742d448ba1d94da10fc1b5c702ecc0388e4a7d1f25' 
  AND token = 'tBkrhHRQciZIvp+IK7DyWlJRkHTioyGMtFuxV2sFEfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}