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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b65d04328647891930c40523abc1ad4c38adb6531426abb5a50ada557b86f4b1' 
  AND token = '6k/U0TNsE6Ihdq0RCmhQcYfTITjRh4z8j3WKV/uuxEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}