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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a059f8f7019e33f771dd17015c9a778c3862c7f5c49cce3d9137974e51b8d604' 
  AND token = 'cQd8n60KqK98A9LW8mpqy/T1JpKavhPrbQyYAjG4mMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}