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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50bb5621b051cab7947bf2a6e20f0a247ad81c7f5d71cc66a84da40c1386e672' 
  AND token = '2qQPwtlz03df3JV5jQsKwa5BrQYTCYuLkU7IxXlNiIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}