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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28a89582b00179db1a60cc2122558f3b0d28730cdffe7dca52a0faffc34fad5f' 
  AND token = 'E7pIIK9ZWlsfbbAuf4yVEag31X1+XgLjsPFhduzJmm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}