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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04373fe73914d007d7c1aebf1c4b89a8e7fb7aefc5baa2421f3eb36694a499f6' 
  AND token = 'xS25Zx+all65POEL8VSzxdR16v0F4fkBDwKH+q9LL3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}