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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af43a3f42ffbdf55e80cafcf5dc47fe902d5d7954af1b1e1f35b844e24edf6aa' 
  AND token = 'M8vmneeG7KjbPk0qM21VCZ3CRDp5NiQt/I3ag7BojaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}