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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ca7c7defcae3ddec369ae1cc2a88f29ae6709c16ecea5aedaa775d2926f4bb0' 
  AND token = 'JnnQnVbhS2YerhDKE5JoCXgOgWqvADJhcM/a+amY9a8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}