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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aef1b3b16ce4f6fcdbc3fd73fe09c836074791df8a5a35cd61ae22d99a176be' 
  AND token = 'ULK3xChO9A8DkPQxTKxAqhit+KvGp/4EWyLeN/zLrd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}