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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cd22c9fe7f78c57b6079900110e6d4c9937861f9cc4c4b689be86368e98cfe4' 
  AND token = 'NM0P49wmkCx/7HjWL4BICYDvi8EFDIylfE5BQo0RAIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}