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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a59665f5af32e716e94ae3434a1a3a8c990a51cb1993c06bab9db6de65e94701' 
  AND token = 'BLbCGulj/r1UvFvczkUiJ+9p9+2fgMy3QcQC7bq0ag8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}