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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c095744a4a17b6ddb1c024d99b1b876891bf7749dddc36762a9731f26b365209' 
  AND token = 'ZmW3gl+MaMG7jW47WkjgcV2bHaoZJVbFdS59WW9qSs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}