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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7380feb99cc03ebf28e7fd1d0cd2fef2e49d80d431d847d7757db5c331304584' 
  AND token = 'ritOdNEtpInIp8CxysbRF35jWrgBBoSkYTt9ulSbAGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}