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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e36153e961d29f7eeefd256af4018be1a67f530fc69717dc72cfc003ffaa2a09' 
  AND token = 'HAn+cL0wv0hYf8IMguWzh3GWVDZ68YTSwLhhe0pTM6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}