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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a991e881eb2b88d0c2c11a4943ed7d1747417ac1d059b71c87aa63ecbc066290' 
  AND token = 'Ct0CnGr6EnkzfsLWWioy2SiOC8pQDXAl5MP+/0oldGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}