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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cff9118e7556c3a844f844f9ddbe838bf78ac3660c4dcadaf8b67b7150dec33' 
  AND token = 'xpwcTleTFb/VoIZpWz8S/6xzTDUYJ4Q/Gdpl85E+YxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}